Macs don't crash much. They also handle themselves well when a ton of apps are running. This was brought home when a co-worker saw me do a Cmd+Tab app switch. Here's a shrunken version of my active app icon bar that popped up.

From left to right:

nvAlt My grimoire and external brain
Sublime Text 2 The go-to text editor
Photoshop CS6 The standard (and last version available without a monthly subscription)
ExtendScript Toolkit For making Photoshop JavaScriptsex
Oxygen XML Editor Totally worth the expensive cost XML tool
iTerm2 The better terminal for Mac
CodeRunner The handy code snippet tester
Chrome Google's Netscape Navigator
Lightroom 5 Main photo workflow tool
Photo Mechanic 5 First step on the photo workflow path
BBEdit Backup text editor
Soulver The reimagined calculator
SQLite Database Browser Way better than the command line (beware sourceforge adons)
Dash The pain reliever for looking at documentation
Finder Apple's happy app
Firefox Mozilla's Netscape Navigator
Safari Apple's Netscape Navigator
DayOne Daily note taking
Preview Non-Adobe PDF viewer
1Password Bringer of sanity and security
ScreenFlow Maker of screencasts
Better Rename 9 Bulk renaming of files without the command line
Spotify The replacement for my 20,000 song mp3 library
System Preferences Machine tweaker
TextExpander Auto-Expander for text snippets
Console The tool to peak behind the machine curtain a little
Terminal For long running items that would be distracting in iTerm2
MAMP Pro The Linux, Apache, MySQL, PHP stack, but for Mac
Stickies Post-it notes for the virtual desktop
OmniFocus A fighting chance against the ever-growing TODO list
Activity Monitor Checking performance when this many apps are running
Contacts Names, numbers, addresses, etc…
Dictionary For those times when auto-correct fails (or you don't trust it)
Transmit FTP, SFTP, etc…
Quicksilver Most used app - Don't let the position in the list fool you
Calendar Days, Weeks, Months… Time flies.
iTunes Relegated to a Podcast tool in the post-Spotify world

Of course, this post wouldn't be complete without also showing the apps running in the menu bar:

Again, from left to right:

Hazel "Automated Organization for your Mac"
LiveReload Reload browsers automatically after editing files (no more constant app switching)
Quicksilver Menubar access to the go-to app launcher
ScreenFlow Not currently recording
DayOne Unnecessary, but doesn't appear to be able to be disabled
TextExpander Menu access to snippets when you forget the keyboard way
Dropzone Drag things here and make them go elsewhere
Divvy Hotkeys for shuffling and positioning windows
Dropbox File syncing done right (referral link)
Monosnap Quick and easy screengrab posting
Alfred Alternate app launcher and automation tool (current overshadowed by Quicksilver)
i1 Profiler Shame on X-rite for not updated software even though the hardware is discontinued
Flycut Continuing the search for a multi-clipboard tool that works with my brain
Caffeine Single click to keep monitor from going to sleep during presentations and processing
Houdini Tries to keep the desktop clean by hiding apps after a time
GeekTool Sends output from scripts to the desktop background
Symantec AntiVirus Must have for the corporate network
1Password Menu bar access to password sanity and security
VMware Fusion To run Linux and Windows machines inside a Mac
Messages Another icon that won't die
MenuMeters The next two icons are: Disk Activity and CPU usage
TimeMachine Only use this if you care about keeping your files and data
Bluetooth status I wonder who came up with the name "Bluetooth"
WiFi status Signal strength at a glance
Volume Don't really need this since I just use the hotkeys
Batter level Figure out technology to make this irrelevant and make a zillion dollars
Keyboard To look up key combos to make letters with umlauts
Date & Time Day of the week I can remember - Day of the month I need help with
Spotlight Haven't been able to kill this one
Notifications Haven't been able to kill this one either

That makes 62 apps (not counting all the behind the scenes stuff). Pretty good considering I haven't rebooted the machine in a month. The negative aspect is that with all this stuff open, I really put off any software updates that require restarting. Based on this XKCD strip, I'm not alone.